REFERENCES:

LUTEIN AND MESO ZEAXANTHIN

(1) Obana A, et al. Effect of an Antioxidant Supplement Containing High Dose Lutein and Zeaxanthin on Macular Pigment and Skin Carotenoid Levels. Sci Rep. 2020 Jun.

LYCIUM BARBARUM

(5) XS M, et al. Lycium Barbarum Polysaccharides Related RAGE and Aβ Levels in the Retina of Mice With Acute Ocular Hypertension and Promote Maintenance of Blood Retinal Barrier. Neural Regen Res. 2020 Dec.

(6) Liu L, et al. Lycium barbarum Polysaccharides Protects Retinal Ganglion Cells Against Oxidative Stress Injury. Neural Regen Res. 2020 Aug.

(8) Neelam K, et al. Fructus lycii: A Natural Dietary Supplement for Amelioration of Retinal Diseases. Nutrients. 2021 Jan.

BLACK CURRANT / BILBERRY

(9) Wang Y, et al. Cyanidin-3-glucoside Attenuates 4-hydroxynonenal- And Visbile Light-Induced Retinal Damage in Vitro and in Vivo. Food Funct. 2019 May.

CARNOSIC ACID

(10) Rezaie T, et al. Protective Effect of Carnosic Acid, a Pro-Electrophilic Compound, in Models of Oxidative Stress and Light-Induced Retinal Degeneration. Invest Ophthalmol Sci.2012 Nov

(11) Wong P, et al. Enhancing the Efficacy of AREDS Antioxidants in Light-Induced Retinal Degeneration. Mol Vis. 2017 Oct.

(12) Albalawi, A. et al. Carnosic Acid Attenuates Acrylamide-Induced Retinal Toxicity in Zebrafish Embryos. Exp Eye Res. 2018 Oct.

APIGENIN

(13) Zhang Y, et al.  Apigenin Protects Mouse Retina Against Oxidative Damage by Regulating the Nrf2 Pathway and Autophagy. Oxid Med Cel Longev. 2020 May.

(14) Abokyi S, et al. Central Role of Oxidative Stress in Age-Related Macular Degeneration: Evidence From a Review of the Molecular Mechanisms and Animal Models. Oxid Med Cell Longev. 2020 Feb

BERBERINE

(15) Li S, et al. Berberine Protects Human Retinal Pigment Epithelial Cells From Hydrogen Peroxide-Induced Oxidative Damage Through Activation of AMPK. Int J Mol Sci. 2018 Jun.

SAFFRON

(16) Maggi M, et al. Saffron: Chemical Composition and Neuroprotective Activity. Molecules. 2020 Nov.

(17) Di Marco S, et al. Saffron: A Multitask Neuroprotective Agent for Retinal Degenerative Diseases. Antioxidants (Basel)  2019 Jul 

(18) Skourtis G, et al. Protective antioxidant effects of saffron extract on retinas of streptozotocin-induced diabetic rats. Rom J Ophthalmol. Oct-Dec 2020

CURCUMIN

(19) Lopez-Malo D, et al. Curcumin as a Therapeutic Option in Retinal Diseases. Antioxidants (Basel). 2020 Jan.